Gene delivery responding to PKA signal using bio-nanocapsule

Jun Oishi, Moeko Ijuin, Jeone Hun Kang, Joohee Jung, Takeshi Mori, Takuro Niidome, Katsuyuki Tanizawa, Kuroda Shun-Ichi, Yoshiki Katayama

研究成果: 会議への寄与タイプ論文

抄録

We recently proposed the novel gene-regulation system responding to cAMP-dependent protein kinase (PKA) and attempted to apply this system to living cell. On the other hand, Kuroda et al has established a gene and drug delivery using bio-nanocapsule (BNC) and the partcles are able to mediate efficient targeted gene delivery to cultured human hepatocytes and to human hepatoma cells in vitro and in vivo. To put our system to practical use, we attempt to combine our PKA responsive gene delivery system with BNC. In this study, we were successful to intracellular signal-responsive regulation of delivered gene-expression in hepatocytes using BNC.

元の言語英語
ページ5365-5366
ページ数2
出版物ステータス出版済み - 12 1 2006
イベント55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, 日本
継続期間: 9 20 20069 22 2006

その他

その他55th Society of Polymer Science Japan Symposium on Macromolecules
日本
Toyama
期間9/20/069/22/06

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Nanocapsules
Genes
Proteins
Gene expression
Drug delivery
Cells
Hepatocytes

All Science Journal Classification (ASJC) codes

  • Engineering(all)

これを引用

Oishi, J., Ijuin, M., Kang, J. H., Jung, J., Mori, T., Niidome, T., ... Katayama, Y. (2006). Gene delivery responding to PKA signal using bio-nanocapsule. 5365-5366. 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.

Gene delivery responding to PKA signal using bio-nanocapsule. / Oishi, Jun; Ijuin, Moeko; Kang, Jeone Hun; Jung, Joohee; Mori, Takeshi; Niidome, Takuro; Tanizawa, Katsuyuki; Shun-Ichi, Kuroda; Katayama, Yoshiki.

2006. 5365-5366 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.

研究成果: 会議への寄与タイプ論文

Oishi, J, Ijuin, M, Kang, JH, Jung, J, Mori, T, Niidome, T, Tanizawa, K, Shun-Ichi, K & Katayama, Y 2006, 'Gene delivery responding to PKA signal using bio-nanocapsule', 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本, 9/20/06 - 9/22/06 pp. 5365-5366.
Oishi J, Ijuin M, Kang JH, Jung J, Mori T, Niidome T その他. Gene delivery responding to PKA signal using bio-nanocapsule. 2006. 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.
Oishi, Jun ; Ijuin, Moeko ; Kang, Jeone Hun ; Jung, Joohee ; Mori, Takeshi ; Niidome, Takuro ; Tanizawa, Katsuyuki ; Shun-Ichi, Kuroda ; Katayama, Yoshiki. / Gene delivery responding to PKA signal using bio-nanocapsule. 論文発表場所 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, 日本.2 p.
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AU - Niidome, Takuro

AU - Tanizawa, Katsuyuki

AU - Shun-Ichi, Kuroda

AU - Katayama, Yoshiki

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