Gene transduction by sonoporation

Sho Ohta; Kentaro Suzuki; Yukiko Ogino; Shinichi Miyagawa; Aki Murashima; Daisuke Matsumaru; Gen Yamada

doi:10.1111/j.1440-169X.2008.01026.x

Gene transduction by sonoporation

Sho Ohta, Kentaro Suzuki, Yukiko Ogino, Shinichi Miyagawa, Aki Murashima, Daisuke Matsumaru, Gen Yamada

研究成果: Contribution to journal › Short survey › 査読

35 被引用数 (Scopus)

抄録

Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

本文言語	英語
ページ（範囲）	517-520
ページ数	4
ジャーナル	Development Growth and Differentiation
巻	50
号	6
DOI	https://doi.org/10.1111/j.1440-169X.2008.01026.x
出版ステータス	出版済み - 8 1 2008
外部発表	はい

All Science Journal Classification (ASJC) codes

発生生物学
細胞生物学

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10.1111/j.1440-169X.2008.01026.x

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AU - Ohta, Sho

AU - Suzuki, Kentaro

AU - Ogino, Yukiko

AU - Miyagawa, Shinichi

AU - Murashima, Aki

AU - Matsumaru, Daisuke

AU - Yamada, Gen

PY - 2008/8/1

Y1 - 2008/8/1

N2 - Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

AB - Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

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U2 - 10.1111/j.1440-169X.2008.01026.x

DO - 10.1111/j.1440-169X.2008.01026.x

M3 - Short survey

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VL - 50

SP - 517

EP - 520

JO - Development Growth and Differentiation

JF - Development Growth and Differentiation

SN - 0012-1592

IS - 6

ER -

Gene transduction by sonoporation

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