Genetically fused charged peptides induce rapid crystallization of proteins

K. Minamihata, K. Tsukamoto, M. Adachi, R. Shimizu, M. Mishina, R. Kuroki, T. Nagamune

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

We utilized electrostatic interaction to induce rapid crystallization of streptavidin. Simply mixing streptavidins possessing either a positively or negatively charged peptide at their C-terminus generated diffraction-quality crystals in a few hours. We modified the streptavidin crystals with fluorescent molecules using biotin, demonstrating the concept of protein crystals as functional biomaterials.

本文言語英語
ページ(範囲)3891-3894
ページ数4
ジャーナルChemical Communications
56
27
DOI
出版ステータス出版済み - 4 7 2020

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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