Genetics of supernumerary tooth formation

Takashi Nakamura, Satoshi Fukumoto

研究成果: Contribution to journalReview article

3 被引用数 (Scopus)

抄録

Tooth development is initiated with placode formation followed by thickening of the oral ectoderm-derived dental epithelium. The dental epithelium then undergoes invagination into the dental mesench-yme, which is derived from the cranial neural crest. The subsequent reciprocal interactions between the dental epithelium and mesenchyme, involving a variety of molecules, are important for tooth morphogenesis, as well as for regulation of tooth number. Recent analyses of mouse mutants have provided important insights into the mechanisms underlying tooth development, including supernumerary tooth formation. In this review, we have discussed the molecular basis for the regulation of tooth number and supernumerary tooth formation.

本文言語英語
ページ(範囲)180-183
ページ数4
ジャーナルjournal of oral biosciences
55
4
DOI
出版ステータス出版済み - 11 2013
外部発表はい

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Dentistry(all)

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