Glucuronidation and the UDP-glucuronosyltransferases in health and disease

Peter G. Wells, Peter I. Mackenzie, Jayanta Roy Chowdhury, Chantal Guillemette, Philip A. Gregory, Yuji Ishii, Antony J. Hansen, Fay K. Kessler, Perry M. Kim, Namita Roy Chowdhury, Joseph K. Ritter

研究成果: ジャーナルへの寄稿学術誌査読

209 被引用数 (Scopus)

抄録

This article is an updated report of a symposium held at the June 2000 annual meeting of the American Society for Pharmacology and Experimental Therapeutics in Boston. The symposium was sponsored by the ASPET Divisions for Drug Metabolism and Molecular Pharmacology. The report covers research from the authors' laboratories on the structure and regulation of UDP-glucuronosyltransferase (UGT) genes, glucuronidation of xenobiotics and endobiotics, the toxicological relevance of UGTs, the role of UGT polymorphisms in cancer susceptibility, and gene therapy for UGT deficiencies.

本文言語英語
ページ(範囲)281-290
ページ数10
ジャーナルDrug Metabolism and Disposition
32
3
DOI
出版ステータス出版済み - 3月 2004

!!!All Science Journal Classification (ASJC) codes

  • 薬理学
  • 薬科学

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