Glycosphingolipids of echinoderms -the chemical diversity of carbohydrate and ceramide structure

Tomofumi Miyamoto, Ryuichi Higuchi

研究成果: ジャーナルへの寄稿評論記事

2 引用 (Scopus)

抄録

Glycosphingolipids (GSLs) are glycoconjugates that consist of sphingosine base, fatty acid, and carbohydrate, and found in cell membranes of living world. Gangliosides are sialoglycolipids that present in the central nervous system, and play critical roles in the physiological properties as carbohydrate antigens, cellular recognition, cell-to-cell communication, receptors of cholera toxin B, differentiation inducer, and so on. Many studies of mammalian gangliosides regarding structures, biosynthesis, metabolism, and functions have been accumulated. On the other hand, in the invertebrates, most of the gangliosides could be found from echinoderms, such as sea urchin, starfish, and sea cucumber, and their chemical structures are quite different from mammalian gangliosides. For nearly 30 years, chemical studies on the GSLs of echinoderms have been carried out in our laboratory. In this paper, we will discuss about the chemical diversity of carbohydrate and ceramide in the GSLs of echinoderms.

元の言語英語
ページ(範囲)501-513
ページ数13
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
68
発行部数5
DOI
出版物ステータス出版済み - 5 1 2010

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Glycosphingolipids
Gangliosides
Ceramides
Carbohydrates
Sphingosine
Glycoconjugates
Biosynthesis
Neurology
Cell membranes
Metabolism
Fatty Acids
Antigens
Communication

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

これを引用

Glycosphingolipids of echinoderms -the chemical diversity of carbohydrate and ceramide structure. / Miyamoto, Tomofumi; Higuchi, Ryuichi.

:: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 巻 68, 番号 5, 01.05.2010, p. 501-513.

研究成果: ジャーナルへの寄稿評論記事

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