Graft-versus-lymphoma effect after reduced intensity allogeneic hematopoietic stem cell transplantation from HLA-two loci mismatched father in a patient with refractory non-Hodgkin lymphoma

Aiko Suminoe, Akinobu Matsuzaki, Yuhki Koga, Miho Hatano, Takuya Hara, Toshiro Hara

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

A 10-year-old female developed a mediastinal mass and was diagnosed as mixed lineage lymphoblastic lymphoma. The tumor was extremely refractory, and she never achieved remission despite intensive therapy using 12 anti-lymphoma agents and local irradiation. She received reduced-intensity allogeneic peripheral blood stem cell transplantation from her HLA-two loci mismatched father, and achieved complete remission. However, the lymphoma relapsed four months later, and we abruptly discontinued immunosuppressive drugs. Concurrent with the development of grade III graft-versus-host disease, the lymphoma completely disappeared with an increase of activated T-cells in peripheral blood. The clinical course suggested the graft-versus-lymphoma effect against aggressive/refractory lymphoma.

元の言語英語
ページ(範囲)500-503
ページ数4
ジャーナルTurkish Journal of Pediatrics
51
発行部数5
出版物ステータス出版済み - 9 1 2009

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Hematopoietic Stem Cell Transplantation
Fathers
Non-Hodgkin's Lymphoma
Lymphoma
Transplants
Peripheral Blood Stem Cell Transplantation
Graft vs Host Disease
Immunosuppressive Agents
Precursor Cell Lymphoblastic Leukemia-Lymphoma
T-Lymphocytes
Pharmaceutical Preparations
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

これを引用

Graft-versus-lymphoma effect after reduced intensity allogeneic hematopoietic stem cell transplantation from HLA-two loci mismatched father in a patient with refractory non-Hodgkin lymphoma. / Suminoe, Aiko; Matsuzaki, Akinobu; Koga, Yuhki; Hatano, Miho; Hara, Takuya; Hara, Toshiro.

:: Turkish Journal of Pediatrics, 巻 51, 番号 5, 01.09.2009, p. 500-503.

研究成果: ジャーナルへの寄稿記事

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