TY - JOUR
T1 - Hemodynamic factors associated with the development of hypertension
AU - shimizu, motohiro
AU - Kario, Kazuomi
PY - 2008/1/1
Y1 - 2008/1/1
N2 - Recent studies have focused on the prevention of hypertension among high-risk, nonhypertensive individuals. In this review, we present that the deficiency of renal sodium excretion, small artery remodeling, and arterial stiffening might be potent mechanisms underlying the development of hypertension. The changes of these hemodynamic factors cause to increase blood pressure, and increasing blood pressure would accelerate those changes again. To break the vicious circle, not only the management of risk factors such as diabetes, obesity, or smoking, but also the intervention with antihypertensive agents is considered as a useful and effective procedure.
AB - Recent studies have focused on the prevention of hypertension among high-risk, nonhypertensive individuals. In this review, we present that the deficiency of renal sodium excretion, small artery remodeling, and arterial stiffening might be potent mechanisms underlying the development of hypertension. The changes of these hemodynamic factors cause to increase blood pressure, and increasing blood pressure would accelerate those changes again. To break the vicious circle, not only the management of risk factors such as diabetes, obesity, or smoking, but also the intervention with antihypertensive agents is considered as a useful and effective procedure.
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M3 - Review article
C2 - 18700550
AN - SCOPUS:52449117060
VL - 66
SP - 1511
EP - 1516
JO - Astrophysical Journal
JF - Astrophysical Journal
SN - 0004-637X
IS - 8
ER -