Hemodynamic responses to visual stimuli in cortex of adults and 3- to 4-year-old children

Gerard B. Remijn, Mitsuru Kikuchi, Yuko Yoshimura, Kiyomi Shitamichi, Sanae Ueno, Kikuko Nagao, Toshio Munesue, Haruyuki Kojima, Yoshio Minabe

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

抜粋

In this study we used near-infrared spectroscopy (NIRS) to measure relative changes in cortical hemodynamics from 19 adult and 19 preschool children (aged 3-4 years old), while they watched epochs of static and motion pictures extracted from TV programs. The spatio-temporal characteristics of oxygenated and deoxygenated hemoglobin volumes (oxy- and deoxy-Hb) of both subject groups were described and compared where appropriate for five regions of interest (ROIs). These were striate, left and right middle temporal, and left and right temporo-parietal areas. Over these areas, deoxy-Hb volumes did not differ between both groups. Preschool data showed significant increases in oxy-Hb over striate, middle temporal and temporo-parietal areas in response to visual motion stimuli. Static stimuli caused a significant oxy-Hb increase over striate and left middle temporal areas. Surprisingly, changes in adult oxy-Hb were not profound and did not show a significant oxy-Hb increase in striate and middle temporal areas in response to the motion stimuli, warranting further research. In spite of oxy-Hb volume differences, oxy-Hb recovery to baseline followed a similar pattern in both groups in response to both static and motion stimuli. Together, the results suggest that near-infrared spectroscopy is a viable method to investigate cortical development of preschool children by monitoring their hemodynamic response patterns.

元の言語英語
ページ(範囲)242-251
ページ数10
ジャーナルBrain Research
1383
DOI
出版物ステータス出版済み - 4 6 2011

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

これを引用

Remijn, G. B., Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., Nagao, K., ... Minabe, Y. (2011). Hemodynamic responses to visual stimuli in cortex of adults and 3- to 4-year-old children. Brain Research, 1383, 242-251. https://doi.org/10.1016/j.brainres.2011.01.090