TY - JOUR
T1 - Heterogeneity and deformation behavior of lipid vesicles
AU - Takiue, Takanori
N1 - Funding Information:
This work was supported in part by the Grant-in-Aid for Scientific Research (B) of Japan Society for the Promotion of Science ( No. 21H01891 ).
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/12
Y1 - 2022/12
N2 - Recent studies on the deformation of lipid vesicles which is a simple model of biological membranes, and the factors that influence it are reviewed. In homogeneous vesicles, the deformation from spherical to various shapes was observed by adjusting the temperature and the osmotic pressure. This is mainly explained by a balance between the bending elasticity and the area difference energy. In phase separated vesicles, the effect of line tension makes a significant contribution to the deformation. In addition, asymmetric distribution of lipid molecules in bilayers caused by lipid sorting determines deformation behaviors including budding, pore, tube, adhesion, and self-reproduction. The change in membrane curvature due to shielding of lipid charges by electrolytes, proteins, peptides, and solid nanoparticles was also reviewed.
AB - Recent studies on the deformation of lipid vesicles which is a simple model of biological membranes, and the factors that influence it are reviewed. In homogeneous vesicles, the deformation from spherical to various shapes was observed by adjusting the temperature and the osmotic pressure. This is mainly explained by a balance between the bending elasticity and the area difference energy. In phase separated vesicles, the effect of line tension makes a significant contribution to the deformation. In addition, asymmetric distribution of lipid molecules in bilayers caused by lipid sorting determines deformation behaviors including budding, pore, tube, adhesion, and self-reproduction. The change in membrane curvature due to shielding of lipid charges by electrolytes, proteins, peptides, and solid nanoparticles was also reviewed.
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U2 - 10.1016/j.cocis.2022.101646
DO - 10.1016/j.cocis.2022.101646
M3 - Review article
AN - SCOPUS:85141503922
SN - 1359-0294
VL - 62
JO - Current Opinion in Colloid and Interface Science
JF - Current Opinion in Colloid and Interface Science
M1 - 101646
ER -