High-resolution three-dimensional diffusion-weighted imaging of middle ear cholesteatoma at 3.0 T MRI: Usefulness of 3D turbo field-echo with diffusion-sensitized driven-equilibrium preparation (TFE-DSDE) compared to single-shot echo-planar imaging

Koji Yamashita, Takashi Yoshiura, Akio Hiwatashi, Makoto Obara, Osamu Togao, Nozomu Matsumoto, Kazufumi Kikuchi, Hiroshi Honda

研究成果: Contribution to journalArticle査読

18 被引用数 (Scopus)

抄録

Objective To prospectively evaluate the usefulness of a newly developed high-resolution three-dimensional diffusion-weighted imaging method, turbo field-echo with diffusion-sensitized driven-equilibrium (TFE-DSDE) in diagnosing middle-ear cholesteatoma by comparing it to conventional single-shot echo-planar diffusion-weighted imaging (SS-EP DWI). Materials and methods Institutional review board approval and informed consent from all participants were obtained. We studied 30 patients with preoperatively suspected acquired cholesteatoma. Each patient underwent an MR examination including both SS-EP DWI and DSDE-TFE using a 3.0 T MR scanner. Images of the 30 patients (60 temporal bones including 30 with and 30 without cholesteatoma) were reviewed by two independent neuroradiologists. The confidence level for the presence of cholesteatoma was graded on a scale of 0-2 (0 = definite absence, 1 = equivocal, 2 = definite presence). Interobserver agreement as well as sensitivity, specificity, and accuracy for detection were assessed for the two reviewers. Results Excellent interobserver agreement was shown for TFE-DSDE (κ = 0.821) whereas fair agreement was obtained for SS-EP DWI (κ = 0.416). TFE-DSDE was associated with significantly higher sensitivity (83.3%) and accuracy (90.0%) compared to SS-EP DWI (sensitivity = 35.0%, accuracy = 66.7%; p < 0.05). No significant difference was found in specificity (96.7% for TFE-DSDE, 98.3% for SS-EP DWI) Conclusion With increased spatial resolution and reduced susceptibility artifacts, TFE-DSDE improves the accuracy in diagnosing acquired middle ear cholesteatomas compared to SS-EP DWI.

本文言語英語
ページ(範囲)e471-e475
ジャーナルEuropean Journal of Radiology
82
9
DOI
出版ステータス出版済み - 9 2013

All Science Journal Classification (ASJC) codes

  • 放射線学、核医学およびイメージング

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