High-throughput injection by circulating plasma-bubbles laden flows

Keishi Ohtonari, Yuta Arakawa, Hiroki Ogata, Daisuke Tujimoto, Yoko Yamanishi

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We have succeeded in injection of plasmid to adherent cells which are suspended in the plasma-bubbles laden circulation flow in a chamber. High-speed plasma-bubbles are generated by glass electrode and the air-liquid interface has a stiction force which draws the gene (plasmid) and stick to the air-liquid interface. The circulating flow increased the chances for cells to contact air-liquid interface of bubbles which is enclosing plasma or reactive gas. Finally, the high reactive interface enables gene transfer to cells efficiently. This proposed two dimensional microfluidic chip contributes to high-throughput gene transfer in bio-medical applications.

本文言語英語
ホスト出版物のタイトル2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016
出版社Institute of Electrical and Electronics Engineers Inc.
ページ144-147
ページ数4
ISBN(電子版)9781509019472
DOI
出版ステータス出版済み - 11 28 2016
外部発表はい
イベント11th IEEE Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016 - Sendai, 日本
継続期間: 4 17 20164 20 2016

その他

その他11th IEEE Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016
国/地域日本
CitySendai
Period4/17/164/20/16

All Science Journal Classification (ASJC) codes

  • 産業および生産工学
  • 機械工学
  • 材料力学
  • 電子材料、光学材料、および磁性材料

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