High-throughput production of satellite-free droplets through a parallelized microfluidic deterministic lateral displacement device

Naotomo Tottori, Takasi Nisisako

研究成果: Contribution to journalArticle査読

20 被引用数 (Scopus)

抄録

We present a parallel numbering-up device for microfluidic production of satellite droplet-free emulsions. The device consists of two stacked layers made of polydimethylsiloxane (PDMS). The bottom layer combines eight parallel sets of a microfluidic droplet generator (MFDG) and deterministic lateral displacement (DLD) array for size-based separation of main and satellite droplets. The top layer has input reservoirs to supply both the disperse and continuous phases evenly to the eight channels of the bottom layer. We employed 3D flow simulations to find the reservoirs most suitable for equal inflow distribution. Water-in-oil (W/O) droplets comprised of main droplets (∼67 μm in diameter) and satellite droplets (1–20 μm) were generated in the parallelized MFDGs, and they were then completely separated through the DLD arrays having a critical diameter of Dc = 37.1 μm. Thus, we confirmed production of satellite droplet-free emulsion droplets at 0.2 ml/h, eight times the processing throughput of single device (= 0.025 ml/h) without decrease in performance.

本文言語英語
ページ(範囲)918-926
ページ数9
ジャーナルSensors and Actuators, B: Chemical
260
DOI
出版ステータス出版済み - 5 1 2018
外部発表はい

All Science Journal Classification (ASJC) codes

  • 電子材料、光学材料、および磁性材料
  • 器械工学
  • 凝縮系物理学
  • 表面、皮膜および薄膜
  • 金属および合金
  • 電子工学および電気工学
  • 材料化学

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