High throughput purification devices for in vivo applications of gene-delivery multifunctional envelope-type nanodevices

Noritada Kaji, Daisuke Shigenaka, Masami Ukawa, Manabu Tokeshi, Hidetaka Akita, Hideyoshi Harashima, Yoshinobu Baba

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We developed microfluidic continuous purification devices based on free-flow electrophoresis for gene-delivery multifunctional envelope-type nanodevices (MEND) which consists of DNA core and phospholipid bilayer envelope. Various impurities, such as DNA, DNA-peptide complex, and liposomes, produced during the fabrication process were removed in an efficient manner and over 75% collection of the input plasmid DNA which corresponds to purified MEND was achieved.

本文言語英語
ホスト出版物のタイトル17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
出版社Chemical and Biological Microsystems Society
ページ1170-1172
ページ数3
ISBN(印刷版)9781632666246
出版ステータス出版済み - 1 1 2013
外部発表はい
イベント17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, ドイツ
継続期間: 10 27 201310 31 2013

出版物シリーズ

名前17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
2

その他

その他17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Countryドイツ
CityFreiburg
Period10/27/1310/31/13

All Science Journal Classification (ASJC) codes

  • Bioengineering

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