Histological grading of malignancy correlates with regional lymph node metastasis and survival of patients with oral squamous cell carcinoma.

H. Kurokawa, Yoshihisa Yamashita, T. Murata, T. Yoshikawa, S. Tokudome, K. Miura, M. Kajiyama

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

抄録

This study evaluated the effectiveness of certain clinical and pathologic parameters in prognosing in oral squamous cell carcinoma (O-SCC). Patients and Methods. We performed a univariate and multivariate analysis of 212 patients with O-SCC and thus determined the move valuable factors in making a prognosis. We then investigated the relationships among the various pathologic parameters and regional lymph node metastasis. Regarding the pathologic parameters, a multivariate analysis using Cox's proportional hazard model determined inflammatory infiltration, invasive tendency, necrotic tendency, mitotic figures, and vascular permeation to be significant and independent prognostic factors affecting O-SCC. In addition, such the pathologic parameters as the mode of invasion, cellular atypia, mitotic figures, a necrotic tendency and as invasive tendency all correlated with the occurrence of regional lymph node metastasis. These statistically estimated histological grading of malignancy was thus found to be clinically acceptable and useful in helping to make a prognosis of O-SCC patients.

元の言語英語
ページ(範囲)225-231
ページ数7
ジャーナルFukuoka igaku zasshi = Hukuoka acta medica
89
発行部数8
出版物ステータス出版済み - 1 1 1998
外部発表Yes

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Squamous Cell Carcinoma
Lymph Nodes
Neoplasm Metastasis
Survival
Neoplasms
Multivariate Analysis
Proportional Hazards Models
Blood Vessels

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Histological grading of malignancy correlates with regional lymph node metastasis and survival of patients with oral squamous cell carcinoma. / Kurokawa, H.; Yamashita, Yoshihisa; Murata, T.; Yoshikawa, T.; Tokudome, S.; Miura, K.; Kajiyama, M.

:: Fukuoka igaku zasshi = Hukuoka acta medica, 巻 89, 番号 8, 01.01.1998, p. 225-231.

研究成果: ジャーナルへの寄稿記事

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abstract = "This study evaluated the effectiveness of certain clinical and pathologic parameters in prognosing in oral squamous cell carcinoma (O-SCC). Patients and Methods. We performed a univariate and multivariate analysis of 212 patients with O-SCC and thus determined the move valuable factors in making a prognosis. We then investigated the relationships among the various pathologic parameters and regional lymph node metastasis. Regarding the pathologic parameters, a multivariate analysis using Cox's proportional hazard model determined inflammatory infiltration, invasive tendency, necrotic tendency, mitotic figures, and vascular permeation to be significant and independent prognostic factors affecting O-SCC. In addition, such the pathologic parameters as the mode of invasion, cellular atypia, mitotic figures, a necrotic tendency and as invasive tendency all correlated with the occurrence of regional lymph node metastasis. These statistically estimated histological grading of malignancy was thus found to be clinically acceptable and useful in helping to make a prognosis of O-SCC patients.",
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T1 - Histological grading of malignancy correlates with regional lymph node metastasis and survival of patients with oral squamous cell carcinoma.

AU - Kurokawa, H.

AU - Yamashita, Yoshihisa

AU - Murata, T.

AU - Yoshikawa, T.

AU - Tokudome, S.

AU - Miura, K.

AU - Kajiyama, M.

PY - 1998/1/1

Y1 - 1998/1/1

N2 - This study evaluated the effectiveness of certain clinical and pathologic parameters in prognosing in oral squamous cell carcinoma (O-SCC). Patients and Methods. We performed a univariate and multivariate analysis of 212 patients with O-SCC and thus determined the move valuable factors in making a prognosis. We then investigated the relationships among the various pathologic parameters and regional lymph node metastasis. Regarding the pathologic parameters, a multivariate analysis using Cox's proportional hazard model determined inflammatory infiltration, invasive tendency, necrotic tendency, mitotic figures, and vascular permeation to be significant and independent prognostic factors affecting O-SCC. In addition, such the pathologic parameters as the mode of invasion, cellular atypia, mitotic figures, a necrotic tendency and as invasive tendency all correlated with the occurrence of regional lymph node metastasis. These statistically estimated histological grading of malignancy was thus found to be clinically acceptable and useful in helping to make a prognosis of O-SCC patients.

AB - This study evaluated the effectiveness of certain clinical and pathologic parameters in prognosing in oral squamous cell carcinoma (O-SCC). Patients and Methods. We performed a univariate and multivariate analysis of 212 patients with O-SCC and thus determined the move valuable factors in making a prognosis. We then investigated the relationships among the various pathologic parameters and regional lymph node metastasis. Regarding the pathologic parameters, a multivariate analysis using Cox's proportional hazard model determined inflammatory infiltration, invasive tendency, necrotic tendency, mitotic figures, and vascular permeation to be significant and independent prognostic factors affecting O-SCC. In addition, such the pathologic parameters as the mode of invasion, cellular atypia, mitotic figures, a necrotic tendency and as invasive tendency all correlated with the occurrence of regional lymph node metastasis. These statistically estimated histological grading of malignancy was thus found to be clinically acceptable and useful in helping to make a prognosis of O-SCC patients.

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