HLA and Graves’ Disease or Diabetes Mellitus in Japan

T. Sasazuki, Y. Kohno, I. Iwamoto, K. Kosaka, K. Okimoto, H. Maruyama, S. Ishiba, J. Konishi, Y. Takeda, S. Naito

研究成果: Contribution to journalLetter査読

22 被引用数 (Scopus)

抄録

To the Editor: A significant increase in the incidence of HLA-B8 and Dw3 has been reported in white patients with several autoimmune diseases, including juvenile-onset diabetes mellitus1 and Graves’ disease.23 Two possibilities to explain this phenomenon have been proposed.4 In the first, these two different organ-specific autoimmune diseases might be associated with the same allele of the same gene, and there might be a common initiating pathogenic event in these diseases; secondly, each of these diseases might be associated with a particular allele of different genes, both of which are in linkage disequilibrium with HLA-B8 and HLA-Dw3. Sasazuki et al.

本文言語英語
ページ(範囲)630-631
ページ数2
ジャーナルNew England Journal of Medicine
298
11
DOI
出版ステータス出版済み - 3 16 1978
外部発表はい

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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