HLA-DPB1*0201 is associated with susceptibility to atopic myelitis in Japanese

Shinya Sato, Noriko Isobe, Satoshi Yoshimura, Yuji Kanamori, Katsuhisa Masaki, Takuya Matsushita, Jun-Ichi Kira

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

抄録

To determine the relationship between susceptibility to atopic myelitis (AM) and polymorphisms of the human leukocyte antigen (HLA)- DPB1 and - DRB1 alleles, we compared each phenotype frequency between 55 AM patients and 367 unrelated healthy controls in Japan. The HLA- DPB1* 0201 allele was significantly more frequent in AM patients than in healthy controls (54.5% vs. 31.9%, corrected P value = 0.0150, odds ratio = 2.564, 95% confidence interval = 1.444-4.554). Our result suggests that the immunogenetic background of AM differs from that of other CNS autoimmune diseases, such as multiple sclerosis and neuromyelitis optica, which show distinct HLA class II associations.

元の言語英語
ページ(範囲)110-113
ページ数4
ジャーナルJournal of Neuroimmunology
251
発行部数1-2
DOI
出版物ステータス出版済み - 10 15 2012

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Myelitis
HLA Antigens
Alleles
Neuromyelitis Optica
Immunogenetics
Central Nervous System Diseases
Autoimmune Diseases
Multiple Sclerosis
Japan
Odds Ratio
Confidence Intervals
Phenotype

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Neurology
  • Clinical Neurology

これを引用

HLA-DPB1*0201 is associated with susceptibility to atopic myelitis in Japanese. / Sato, Shinya; Isobe, Noriko; Yoshimura, Satoshi; Kanamori, Yuji; Masaki, Katsuhisa; Matsushita, Takuya; Kira, Jun-Ichi.

:: Journal of Neuroimmunology, 巻 251, 番号 1-2, 15.10.2012, p. 110-113.

研究成果: ジャーナルへの寄稿記事

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AU - Masaki, Katsuhisa

AU - Matsushita, Takuya

AU - Kira, Jun-Ichi

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