HLA‐DR MT and MB antigens in Takayasu disease

Fujio Numano, Ichiro Isohisa, Michiko Egami, Nobuo Ohta, Takehiko Sasazuki

研究成果: ジャーナルへの寄稿学術誌査読

16 被引用数 (Scopus)

抄録

Recent studies on the pathogenesis of Takayasu disease have focussed on the participation of genetic factors, and HLA analysis has confirmed the close relationship between Takayasu disease and HLA Bw52. In an attempt to investigate the association of immune response gene with the disease, HLA‐DR (DR‐1, −2, −3, −4, −5, ‐w6, −7, ‐w8, ‐w9, ‐w10), MT (‐1, −2, −3), MB (‐1, −3) antigens were studied in 52 patients with Takayasu disease and the data compared with findings in healthy Japanese. As there were no statistical differences between the two groups in the frequencies of all these antigens, genetic factors in Takayasu disease may be much more closely associated with B than with D loci.

本文言語英語
ページ(範囲)208-212
ページ数5
ジャーナルTissue antigens
21
3
DOI
出版ステータス出版済み - 1月 1 1983
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 免疫アレルギー学
  • 免疫学
  • 生化学
  • 遺伝学

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