How to diagnose polysulphide poisoning from tissue samples

T. Nagata, S. Kage, K. Kimura, K. Kudo, T. Imamura

研究成果: ジャーナルへの寄稿学術誌査読

13 被引用数 (Scopus)


We carried out animal experiments to toxicologically verify polysulphide poisoning by analyzing tissue samples. A bathing agent containing calcium polysulphides was administered orally to rats, and then polysulphides and sulphide, the decomposed product of polysulphides, were analyzed by GC and GC/MS. The concentrations of polysulphides (μmol/ml or g) were found to be highest in blood (0.196), followed by the liver (0.051), the lungs (0.018) and kindneys (0.013), but were below the detection limit (0.005 μmol/g) in the other tissues tested. Sulphide was detected in all the tissue samples and was found to be highest in the blood (0.518 μmol/ml), this being 40 times higher than that required for fatal poisoning in the case of hydrogen sulphide. Polysulphide poisoning was considered to be confirmatively diagnosed by detecting and measuring polysuphides and supplementarily sulphide in body tissues, most pertinently in the blood. Two practical cases of suspected poisoning by polysulphides are briefly described.

ジャーナルInternational Journal of Legal Medicine
出版ステータス出版済み - 11月 1994

!!!All Science Journal Classification (ASJC) codes

  • 病理学および法医学


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