How to quantitatively synthesize dynamic changes in arterial pressure from baroreflexly modulated ventricular and arterial properties

takafumi sakamoto, Yoshinori Murayama, Tomoyuki Tobushi, Kazuo Sakamoto, Atsushi Tanaka, Takaki Tsutsumi, Kenji Sunagawa

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

Baroreflex regulates arterial pressure by modulating ventricular and vascular properties. We investigated if the framework of circulatory equilibrium that we developed previously (Am J Physiol 2004, 2005) by extending the classic Guyton's framework is capable of predicting baroreflex induced changes in arterial pressure. In animal experiments, we estimated open loop transfer functions of baroreflexly modulated ventricular and vascular properties, synthesized baroreflex induced dynamic changes in arterial pressure using the estimated transfer functions and compared the predicted responses with measured responses. We demonstrated that the predicted baroreflex induced changes in arterial pressure matched reasonable well with those measured. We conclude that the framework of circulatory equilibrium is generalizable under the condition where baroreflex dynamically changes arterial pressure.

本文言語英語
ホスト出版物のタイトル2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
ページ2869-2871
ページ数3
DOI
出版ステータス出版済み - 12 1 2010
イベント2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, アルゼンチン
継続期間: 8 31 20109 4 2010

その他

その他2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Countryアルゼンチン
CityBuenos Aires
Period8/31/109/4/10

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Health Informatics

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