Hydration Mechanism in Blood-Compatible Polymers Undergoing Phase Separation

Daiki Murakami, Kosuke Yamazoe, Shin Nosuke Nishimura, Naoya Kurahashi, Tomoya Ueda, Jun Miyawaki, Yuka Ikemoto, Masaru Tanaka, Yoshihisa Harada

研究成果: ジャーナルへの寄稿学術誌査読

2 被引用数 (Scopus)

抄録

Interactions involving intermediate water are crucial for the design of novel blood-compatible materials. Herein, we use a combination of atomic force microscopy, quartz crystal microbalance measurements, and soft X-ray emission spectroscopy to investigate the local hydrogen-bonded configuration of water on blood-compatible poly(2-methoxyethyl acrylate) and non-blood-compatible poly(n-butyl acrylate) grafted on a gold substrate. We find that the initially incorporated water induces polymer-dependent phase separation, facilitating further water uptake. For the blood-compatible polymer, tetrahedrally coordinated water coexists with water adsorbed on C═O groups in low-density regions of the grafted polymer surface, providing a scaffold for the formation of intermediate water. The amount of intermediate water is determined by the type of functional groups, local polymer configuration, and polymer morphology. Thus, blood compatibility is governed by the complex water/polymer interactions.

本文言語英語
ページ(範囲)1090-1098
ページ数9
ジャーナルLangmuir
38
3
DOI
出版ステータス出版済み - 1月 25 2022

!!!All Science Journal Classification (ASJC) codes

  • 材料科学(全般)
  • 凝縮系物理学
  • 表面および界面
  • 分光学
  • 電気化学

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