Hydrosilane Reduction of Nitriles to Primary Amines by Cobalt-Isocyanide Catalysts

Atsushi Sanagawa, Hideo Nagashima

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

抄録

Reduction of nitriles to silylated primary amines was achieved by combination of 1,1,3,3-tetramethyldisiloxane (TMDS) as the hydrosilane and a catalytic amount of Co(OPIV) 2 (PIV = CO t Bu) associated with isocyanide ligands. The resulting silylated amines were subjected to acid hydrolysis or treatment with acid chlorides to give the corresponding primary amines or imides in good yields. One-pot synthesis of primary amides to primary amines with hydrosilanes was also achieved by iron-cobalt dual catalyst systems.

元の言語英語
ページ(範囲)287-291
ページ数5
ジャーナルOrganic Letters
21
発行部数1
DOI
出版物ステータス出版済み - 1 4 2019

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Nitriles
nitriles
Cyanides
Cobalt
Amines
amines
cobalt
catalysts
Catalysts
Imides
acids
Acids
imides
Carbon Monoxide
particle image velocimetry
Amides
amides
hydrolysis
Chlorides
Hydrolysis

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

これを引用

Hydrosilane Reduction of Nitriles to Primary Amines by Cobalt-Isocyanide Catalysts. / Sanagawa, Atsushi; Nagashima, Hideo.

:: Organic Letters, 巻 21, 番号 1, 04.01.2019, p. 287-291.

研究成果: ジャーナルへの寄稿記事

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