Hydroxyapatite hybridized with metal oxides for biomedical applications

Akiyoshi Osaka, Eiji Fujii, Koji Kawabata, Hideyuki Yoshimatsu, Satoshi Hayakawa, Kanji Tsuru, Christian Bonhomme, Florence Babonneau

研究成果: 著書/レポートタイプへの貢献会議での発言

抜粋

Zn-substituted apatites with homogeneous Zn distribution in the particles (ZnΦHAp) and those with graded distribution (Zn/HAp) were prepared via a conventional wet chemical synthesis and soaking the Zn-free apatite particles in zinc nitrate solutions: X-ray photoelectron spectra of the apatites confirmed such Zn distribution. Physical and chemical properties such as particle size, specific surface area, or zeta-potential and were correlated to adsorption of β2-microglobulin (β2-MG) and bovine serum albumin (BSA). Adsorption of β2-MG on both apatites increased with the Zn content, whereas more β2-MG was adsorbed on Zn/HAp than on ZnΦHAp. The amount of BSA adsorbed on ZnΦHAp reached a maximum at about 1.5%, while it remained constant for Zn/HAp. From the results, it was suggested that Zn-substituted sites had better affinity against β2-MG and favored β2-MG adsorption. Surface charge on the particles was one of the factors to explain the suppressed adsorption of BSA by both apatites.

元の言語英語
ホスト出版物のタイトルAdvances in Bioceramics and Biocomposites II - A Collection of Papers Presented at the 30th International Conference on Advanced Ceramics and Composites
ページ39-47
ページ数9
エディション6
出版物ステータス出版済み - 12 1 2006
イベントAdvances in Bioceramics and Biocomposites II - 30th International Conference on Advanced Ceramics and Composites - Cocoa Beach, FL, 米国
継続期間: 1 22 20061 27 2006

出版物シリーズ

名前Ceramic Engineering and Science Proceedings
番号6
27
ISSN(印刷物)0196-6219

その他

その他Advances in Bioceramics and Biocomposites II - 30th International Conference on Advanced Ceramics and Composites
米国
Cocoa Beach, FL
期間1/22/061/27/06

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Materials Chemistry

これを引用

Osaka, A., Fujii, E., Kawabata, K., Yoshimatsu, H., Hayakawa, S., Tsuru, K., ... Babonneau, F. (2006). Hydroxyapatite hybridized with metal oxides for biomedical applications. : Advances in Bioceramics and Biocomposites II - A Collection of Papers Presented at the 30th International Conference on Advanced Ceramics and Composites (6 版, pp. 39-47). (Ceramic Engineering and Science Proceedings; 巻数 27, 番号 6).