Hypoosmotic stress induces flagellar biosynthesis and swimming motility in Escherichia albertii

Tetsuya Ikeda, Toshie Shinagawa, Takuya Ito, Yuta Ohno, Akiko Kubo, Junichiro Nishi, Yasuhiro Gotoh, Yoshitoshi Ogura, Tadasuke Ooka, Tetsuya Hayashi

研究成果: ジャーナルへの寄稿記事

抜粋

Bacteria use flagella as propellers to move to favorable environments. Escherichia albertii, a growing cause of foodborne illness and diarrhea, is reportedly non-motile and lacks flagella on its surface. Here, we report that 27 out of 59 E. albertii strains, collected mainly from humans and birds, showed swimming motility when cultured at low osmotic pressure. The biosynthesis of flagella in E. albertii cells was induced under ambient temperature and hypoosmotic pressure: conditions which resemble aquatic environments. Flagellar induction increased E. albertii survival in the intestinal epithelial cell culture containing gentamicin. Although genes involved in chemotaxis are not present in the E. albertii genome, the addition of glutamic acid, an amino acid known to regulate the internal cell osmolarity, augmented the proportion of swimming cells by 35-fold. These results suggest that flagellar biosynthesis and motility in E. albertii cells are controlled by their internal and external osmolarity.

元の言語英語
記事番号87
ジャーナルCommunications Biology
3
発行部数1
DOI
出版物ステータス出版済み - 12 1 2020

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • Medicine (miscellaneous)

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