Identification and characterization of the fusion transcript, composed of the apterous homolog and a putative protein phosphatase gene, generated by 1.5-Mb interstitial deletion in the vestigial (Vg) mutant of Bombyx mori

T. Fujii, H. Abe, S. Katsuma, T. Shimada

研究成果: ジャーナルへの寄稿学術誌査読

4 被引用数 (Scopus)

抄録

The vestigial (Vg) mutant is a Z-linked mutant that causes vestigial wings in the silkworm, Bombyx mori. We have previously reported a 1.5-Mb interstitial deletion on the Z chromosome bearing the Vg mutation (ZVg chromosome). In this study, we found that exons 3-8 of a gene named Bmptp-Z encoding a putative tyrosine-specific protein phosphatase are deleted by the 1.5-Mb interstitial deletion. We found that a gene encoding the Bombyx homolog of Drosophila Apterous (BmAp-A) protein is located 4.5 kb downstream of the distal breakpoint of the 1.5-Mb interstitial deletion. Moreover, an in-frame fusion transcript composed of the 5' part of Bmptp-Z and the 3' part of Bmap-A is generated specific to the ZVg chromosome. Effects of the in-frame fusion transcript on the vestigial phenotype are discussed.

本文言語英語
ページ(範囲)306-312
ページ数7
ジャーナルInsect Biochemistry and Molecular Biology
41
5
DOI
出版ステータス出版済み - 5月 2011
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 生化学
  • 分子生物学
  • 昆虫科学

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