Identification of a frameshift mutation resulting in premature termination and loss of cell wall anchoring of the PAc antigen of Streptococcus mutans GS-5

Y. Murakami, Y. Nakano, Y. Yamashita, T. Koga

研究成果: Contribution to journalArticle査読

32 被引用数 (Scopus)

抄録

Most strains of Streptococcus mutans possess a 190-kDa protein antigen (PAc) on their cell surfaces, while strain GS-5 produces extracellularly a 155-kDa PAc protein. The pac gene of strain GS-5 consists of 3,477 bp and codes for a protein of 1,158 amino acids. One insertion of an adenine into the 3,469th, 3,470th, or 3,471st position from the start codon results in a frameshift mutation at codon 1157 with subsequent termination after 3 additional codons.

本文言語英語
ページ(範囲)794-797
ページ数4
ジャーナルInfection and Immunity
65
2
DOI
出版ステータス出版済み - 1997

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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