TY - JOUR
T1 - Imaging features of undifferentiated carcinoma of the pancreas
AU - Ishigami, Kousei
AU - Nishie, Akihiro
AU - Yamamoto, Takeo
AU - Asayama, Yoshiki
AU - Ushijima, Yasuhiro
AU - Kakihara, Daisuke
AU - Fujita, Nobuhiro
AU - Morita, Koichiro
AU - Takao, Ohtsuka
AU - Kawabe, Ken
AU - Mochidome, Naoki
AU - Honda, Hiroshi
N1 - Funding Information:
The authors greatly thank Dr. Yoshinao Oda, M.D., Ph.D., Professor and Chairman of the Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, for providing pathology specimens and Dr. Masafumi Nakamura, M.D. and Ph.D., Professor and Chairman of the Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, for providing cases.
Publisher Copyright:
© 2019 The Royal Australian and New Zealand College of Radiologists
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Introduction: The purpose of this retrospective study was to evaluate imaging features of undifferentiated carcinoma of the pancreas. Methods: The study group included eight patients with surgically resected undifferentiated carcinoma of the pancreas. Multidetector-row computed tomography (MDCT, n = 8) and magnetic resonance imaging (MRI, n = 6) findings were retrospectively reviewed. Results: On MDCT, all eight cases were hypovascular with upstream main pancreatic duct (MPD) dilatation, and only 1 showed exophytic growth. Five cases (62.5%) showed necrosis/cystic change, and calcification was observed in two cases (25%). Calcification reflected tumour osteoid components. On MRI, haemorrhage and hemosiderin were observed in 4 of 6 (66.7%) cases. In addition, tumour thrombus in the splenic vein (n = 1) and intraductal tumour growth in the MPD (n = 2) were pathologically identified, although imaging studies only revealed 1 of these latter cases. Conclusion: Undifferentiated carcinoma of the pancreas may present as a tumour with haemorrhagic necrosis. Coexistence of calcification, intraductal tumour growth in the MPD and tumour thrombus may support the imaging diagnosis of this entity.
AB - Introduction: The purpose of this retrospective study was to evaluate imaging features of undifferentiated carcinoma of the pancreas. Methods: The study group included eight patients with surgically resected undifferentiated carcinoma of the pancreas. Multidetector-row computed tomography (MDCT, n = 8) and magnetic resonance imaging (MRI, n = 6) findings were retrospectively reviewed. Results: On MDCT, all eight cases were hypovascular with upstream main pancreatic duct (MPD) dilatation, and only 1 showed exophytic growth. Five cases (62.5%) showed necrosis/cystic change, and calcification was observed in two cases (25%). Calcification reflected tumour osteoid components. On MRI, haemorrhage and hemosiderin were observed in 4 of 6 (66.7%) cases. In addition, tumour thrombus in the splenic vein (n = 1) and intraductal tumour growth in the MPD (n = 2) were pathologically identified, although imaging studies only revealed 1 of these latter cases. Conclusion: Undifferentiated carcinoma of the pancreas may present as a tumour with haemorrhagic necrosis. Coexistence of calcification, intraductal tumour growth in the MPD and tumour thrombus may support the imaging diagnosis of this entity.
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U2 - 10.1111/1754-9485.12925
DO - 10.1111/1754-9485.12925
M3 - Article
C2 - 31268241
AN - SCOPUS:85068515570
VL - 63
SP - 580
EP - 588
JO - Journal of the College of Radiologists of Australasia
JF - Journal of the College of Radiologists of Australasia
SN - 1754-9477
IS - 5
ER -