Immune response to Streptococcus pyogenes and the susceptibility to psoriasis

Masahiko Muto; Yoshihisa Fujikura; Yoshiaki Hamamoto; Makoto Ichimiya; Akiko Ohmura; Takehiko Sasazuki; Tetsuo Fukumoto; Chidori Asagami

doi:10.1111/j.1440-0960.1996.tb01087.x

Immune response to Streptococcus pyogenes and the susceptibility to psoriasis

Masahiko Muto, Yoshihisa Fujikura, Yoshiaki Hamamoto, Makoto Ichimiya, Akiko Ohmura, Takehiko Sasazuki, Tetsuo Fukumoto, Chidori Asagami

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

11 被引用数 (Scopus)

抄録

Monoclonal antibodies directed against type 12 Group A streptococcal cell wall antigens cross-react with nuclei and cytoplasm of cells from skin and synovium from controls, uninvolved skin of psoriatics and psoriatic plaques. Patients with psoriasis had high serum titres of antibody against the M12 (C-region) streptococcal antigen compared to controls. An abnormal immune response directed against a 'self' antigen after initiation by Group A streptococcal infection may play an important role in the exacerbation or development of psoriasis.

本文言語	英語
ページ（範囲）	S54-S55
ジャーナル	Australasian Journal of Dermatology
巻	37
号	SUPPL. 1
DOI	https://doi.org/10.1111/j.1440-0960.1996.tb01087.x
出版ステータス	出版済み - 1996
外部発表	はい

!!!All Science Journal Classification (ASJC) codes

皮膚病学

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10.1111/j.1440-0960.1996.tb01087.x

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title = "Immune response to Streptococcus pyogenes and the susceptibility to psoriasis",

abstract = "Monoclonal antibodies directed against type 12 Group A streptococcal cell wall antigens cross-react with nuclei and cytoplasm of cells from skin and synovium from controls, uninvolved skin of psoriatics and psoriatic plaques. Patients with psoriasis had high serum titres of antibody against the M12 (C-region) streptococcal antigen compared to controls. An abnormal immune response directed against a 'self' antigen after initiation by Group A streptococcal infection may play an important role in the exacerbation or development of psoriasis.",

author = "Masahiko Muto and Yoshihisa Fujikura and Yoshiaki Hamamoto and Makoto Ichimiya and Akiko Ohmura and Takehiko Sasazuki and Tetsuo Fukumoto and Chidori Asagami",

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doi = "10.1111/j.1440-0960.1996.tb01087.x",

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T1 - Immune response to Streptococcus pyogenes and the susceptibility to psoriasis

AU - Muto, Masahiko

AU - Fujikura, Yoshihisa

AU - Hamamoto, Yoshiaki

AU - Ichimiya, Makoto

AU - Ohmura, Akiko

AU - Sasazuki, Takehiko

AU - Fukumoto, Tetsuo

AU - Asagami, Chidori

PY - 1996

Y1 - 1996

N2 - Monoclonal antibodies directed against type 12 Group A streptococcal cell wall antigens cross-react with nuclei and cytoplasm of cells from skin and synovium from controls, uninvolved skin of psoriatics and psoriatic plaques. Patients with psoriasis had high serum titres of antibody against the M12 (C-region) streptococcal antigen compared to controls. An abnormal immune response directed against a 'self' antigen after initiation by Group A streptococcal infection may play an important role in the exacerbation or development of psoriasis.

AB - Monoclonal antibodies directed against type 12 Group A streptococcal cell wall antigens cross-react with nuclei and cytoplasm of cells from skin and synovium from controls, uninvolved skin of psoriatics and psoriatic plaques. Patients with psoriasis had high serum titres of antibody against the M12 (C-region) streptococcal antigen compared to controls. An abnormal immune response directed against a 'self' antigen after initiation by Group A streptococcal infection may play an important role in the exacerbation or development of psoriasis.

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DO - 10.1111/j.1440-0960.1996.tb01087.x

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AN - SCOPUS:0242463669

SN - 0004-8380

VL - 37

SP - S54-S55

JO - Australasian Journal of Dermatology

JF - Australasian Journal of Dermatology

IS - SUPPL. 1

ER -

Immune response to Streptococcus pyogenes and the susceptibility to psoriasis

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!!!All Science Journal Classification (ASJC) codes

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