Immunofluorescent studies of fibronectin and laminin in the human eye

T. Kohno, N. Sorgente, T. Ishibashi, R. Goodnight, S. J. Ryan

研究成果: Contribution to journalArticle査読

187 被引用数 (Scopus)

抄録

The topographic distribution of fibronectin and laminin in young and old human eyes was determined by indirect immunofluorescent techniques. These two glycoproteins may play a role in the attachment of the vitreous to the internal limiting membrane (ILM) and the internal limiting membrane to the Mueller cell processes. A double-laminated pattern of fluorescence for both glycoproteins was frequently found at the ILM of the posterior retina of aged eyes. This pattern of fluorescence, which was rarely seen in young eyes, may represent senescent changes in the ILM which could predispose the eye to posterior vitreous detachment.

本文言語英語
ページ(範囲)506-514
ページ数9
ジャーナルInvestigative Ophthalmology and Visual Science
28
3
出版ステータス出版済み - 1987
外部発表はい

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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