Immunohistochemical expression of β-human chorionic gonadotropin in colorectal carcinoma

Akinori Kido, Masaki Mori, Yosuke Adachi, Hirofumi Yukaya, Teruyoshi Ishida, Keizo Sugimachi

研究成果: ジャーナルへの寄稿学術誌査読

17 被引用数 (Scopus)

抄録

The presence of human β-chorionic gonadotropin (HCG) was immunohistochemically studied in 123 cases of primary colorectal carcinoma using the avidin-biotin-peroxidase complex method. Positive staining for HCG was recognized in 45 (36.6%) tumors and a statistical difference was observed between the HCG-positive (n = 45) and -negative (n = 78) groups concerning the frequency of blood vessel invasion in the primary tumor (P< 0.01). The prognosis fur patients with HCG-positive carcinoma was thus significantly worse than that for patients with HCG-negative carcinoma (P < 0.05). A multivariate analysis using the Cox hazards model demonstrated the positive or negative staining of HCG to be one of the independent prognostic factors. The above findings show that, in addition to various other prognostic factors, the HCG staining status may thus also help in determining the prognosis of patients with primary colorectal carcinoma.

本文言語英語
ページ(範囲)966-970
ページ数5
ジャーナルSurgery today
26
12
DOI
出版ステータス出版済み - 1996

!!!All Science Journal Classification (ASJC) codes

  • 外科

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