Immunotherapy approaches targeting regulatory T-cells

Hideya Onishi, Takashi Morisaki, Mitsuo Katano

研究成果: Contribution to journalReview article査読

16 被引用数 (Scopus)

抄録

The immune system prevents establishment and progression of cancer through innate and adaptive surveillance. However, some cancerous cells successfully evade the immune system. Regulatory T-cells (Tregs) facilitate such evasion. Tregs may be the factor responsible for the limited success of human tumor immunotherapy to date. To improve immunotherapy, it is thought that the number of Tregs and their functions should be inhibited in patients with advanced cancer. In this review, we focus on recent immunotherapy efforts targeting Tregs.

本文言語英語
ページ(範囲)997-1003
ページ数7
ジャーナルAnticancer research
32
3
出版ステータス出版済み - 3 2012
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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