Impact of donor age and recipient status on left-lobe graft for living donor adult liver transplantation

Tomoharu Yoshizumi, Akinobu Taketomi, Yuji Soejima, Hideaki Uchiyama, Toru Ikegami, Noboru Harada, Hiroto Kayashima, Yo Ichi Yamashita, Mitsuo Shimada, Yoshihiko Maehara

研究成果: ジャーナルへの寄稿学術誌査読

54 被引用数 (Scopus)

抄録

Donor safety is the priority when performing a living donor adult liver transplantation (LDALT). We herein present our findings using left-lobe graft in LDALT. Data on 119 recipients who underwent the LDALT, and on 119 donors who underwent extended left lobectomy were reviewed. The recipients were divided into groups above (n = 19) and below (n = 100) 50 years of donor age, into groups above (n = 63) and below (n = 56) 40% of graft size (graft volume/standard liver volume, GV/SLV), and above (n = 25) and below (n = 94) 20 of pre-operative model for end-stage liver disease (MELD). Total bilirubin (TB), volume of ascites, prothrombin time international normalized ratio on postoperative day 14 or survival rates were compared. TB (mg/dl) or volume of ascites (ml) of the group in donor age < 50 years was better than that of the group in donor age ≥ 50 years (7.4 vs. 14.7 or 788 vs. 1379, P < 0.001 or P < 0.005, respectively). The graft and patient survival rates of the lower MELD group tended to be better than that of the higher MELD group. LDALT can be safely performed using a left-lobe graft. However, when using the graft from the donor ≥ 50 years, especially for the recipients with the MELD ≥ 20, the indications should be carefully discussed.

本文言語英語
ページ(範囲)81-88
ページ数8
ジャーナルTransplant International
21
1
DOI
出版ステータス出版済み - 1月 2008

!!!All Science Journal Classification (ASJC) codes

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