Impact of interstitial changes on radiation pneumonitis after stereotactic body radiation therapy for lung cancer

Tadamasa Yoshitake, Yoshiyuki Shioyama, Kaori Asai, Katsumasa Nakamura, Tomonari Sasaki, Saiji Ohga, Takeshi Kamitani, Toshihiro Yamaguchi, Kaori Ohshima, Keiji Matsumoto, Satoshi Kawanami, Hiroshi Honda

研究成果: Contribution to journalArticle査読

23 被引用数 (Scopus)

抄録

Aim: The aim of the present study was to evaluate the impact of interstitial changes (IC) on radiation pneumonitis (RP) after stereotactic body radiation therapy (SBRT) for lung cancer. Patients and Methods: We analyzed 260 consecutive patients with primary lung cancer treated with SBRT. According to the presence or absence of IC on the pre-treatment computed tomography, patients were divided into two groups: an IC group (n=18) and a non-IC group (n=242). Results: RP of grade 2 or more was observed in 9 (50.0%) and 14 (6.7%) patients in the IC and non-IC group, respectively. All three patients with grade 5 RP were in the IC group. As indicated by multivariate analysis, the presence of IC was the only significant predictive factor of RP of grade 2 or more. Conclusion: The presence of IC was a significant indicator of grade 2 or more RP after SBRT for patients with lung cancer.

本文言語英語
ページ(範囲)4909-4914
ページ数6
ジャーナルAnticancer research
35
9
出版ステータス出版済み - 9 1 2015

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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