Impact of nutrition in the treatment of congenital diaphragmatic hernia

Keita Terui, Noriaki Usui, Yuko Tazuke, Kouji Nagata, Miharu Ito, Hiroomi Okuyama, Masahiro Hayakawa, Tomoaki Taguchi, Yasunori Sato, Hideo Yoshida

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

Background: The optimum enteral (EN) and parenteral nutrition (PN) regimens during acute management of congenital diaphragmatic hernia (CDH) remain unclear. We examined the effects of EN and PN on weight gain in CDH patients. Methods: A multicenter retrospective cohort study of neonates with CDH (born 2006–2010; n = 105) who survived to discharge was conducted. Patients were divided as receiving PN ≥ or <50 kcal/kg/day at 1 week of age, and EN ≥ or <60 kcal/kg/day at 2 weeks of age. Changes in bodyweight at 30, 60, and 90 days of age were compared. Results: The higher EN group (n = 39) had greater mean weight gain than the lower EN group (n = 66; 90 days: 2,501 g, 95% CI: 2,294–2,710 g vs 1,706 g, 95% CI: 1,553–1,861 g; P <0.001). When patients received lower EN, the higher PN group (n = 24) had greater mean weight gain than the lower PN group (n = 42; 90 days: 1,768 g, 95% CI: 1,574–1,961 g vs 1,411 g, 95% CI: 1,264–1,558 g; P = 0.004). Conclusion: The amount of EN in the acute phase of CDH management is essential for weight gain during infancy. When patients are intolerant to adequate EN, supportive PN is also essential.

元の言語英語
ページ(範囲)482-488
ページ数7
ジャーナルPediatrics International
61
発行部数5
DOI
出版物ステータス出版済み - 5 1 2019

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Parenteral Nutrition
Small Intestine
Weight Gain
Enteral Nutrition
Therapeutics
Congenital Diaphragmatic Hernias
Cohort Studies
Retrospective Studies
Newborn Infant

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

これを引用

Terui, K., Usui, N., Tazuke, Y., Nagata, K., Ito, M., Okuyama, H., ... Yoshida, H. (2019). Impact of nutrition in the treatment of congenital diaphragmatic hernia. Pediatrics International, 61(5), 482-488. https://doi.org/10.1111/ped.13837

Impact of nutrition in the treatment of congenital diaphragmatic hernia. / Terui, Keita; Usui, Noriaki; Tazuke, Yuko; Nagata, Kouji; Ito, Miharu; Okuyama, Hiroomi; Hayakawa, Masahiro; Taguchi, Tomoaki; Sato, Yasunori; Yoshida, Hideo.

:: Pediatrics International, 巻 61, 番号 5, 01.05.2019, p. 482-488.

研究成果: ジャーナルへの寄稿記事

Terui, K, Usui, N, Tazuke, Y, Nagata, K, Ito, M, Okuyama, H, Hayakawa, M, Taguchi, T, Sato, Y & Yoshida, H 2019, 'Impact of nutrition in the treatment of congenital diaphragmatic hernia', Pediatrics International, 巻. 61, 番号 5, pp. 482-488. https://doi.org/10.1111/ped.13837
Terui K, Usui N, Tazuke Y, Nagata K, Ito M, Okuyama H その他. Impact of nutrition in the treatment of congenital diaphragmatic hernia. Pediatrics International. 2019 5 1;61(5):482-488. https://doi.org/10.1111/ped.13837
Terui, Keita ; Usui, Noriaki ; Tazuke, Yuko ; Nagata, Kouji ; Ito, Miharu ; Okuyama, Hiroomi ; Hayakawa, Masahiro ; Taguchi, Tomoaki ; Sato, Yasunori ; Yoshida, Hideo. / Impact of nutrition in the treatment of congenital diaphragmatic hernia. :: Pediatrics International. 2019 ; 巻 61, 番号 5. pp. 482-488.
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abstract = "Background: The optimum enteral (EN) and parenteral nutrition (PN) regimens during acute management of congenital diaphragmatic hernia (CDH) remain unclear. We examined the effects of EN and PN on weight gain in CDH patients. Methods: A multicenter retrospective cohort study of neonates with CDH (born 2006–2010; n = 105) who survived to discharge was conducted. Patients were divided as receiving PN ≥ or <50 kcal/kg/day at 1 week of age, and EN ≥ or <60 kcal/kg/day at 2 weeks of age. Changes in bodyweight at 30, 60, and 90 days of age were compared. Results: The higher EN group (n = 39) had greater mean weight gain than the lower EN group (n = 66; 90 days: 2,501 g, 95{\%} CI: 2,294–2,710 g vs 1,706 g, 95{\%} CI: 1,553–1,861 g; P <0.001). When patients received lower EN, the higher PN group (n = 24) had greater mean weight gain than the lower PN group (n = 42; 90 days: 1,768 g, 95{\%} CI: 1,574–1,961 g vs 1,411 g, 95{\%} CI: 1,264–1,558 g; P = 0.004). Conclusion: The amount of EN in the acute phase of CDH management is essential for weight gain during infancy. When patients are intolerant to adequate EN, supportive PN is also essential.",
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AU - Terui, Keita

AU - Usui, Noriaki

AU - Tazuke, Yuko

AU - Nagata, Kouji

AU - Ito, Miharu

AU - Okuyama, Hiroomi

AU - Hayakawa, Masahiro

AU - Taguchi, Tomoaki

AU - Sato, Yasunori

AU - Yoshida, Hideo

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