Impact of obesity on the surgical outcome following repeat hepatic resection in Japanese patients with recurrent hepatocellular carcinoma

Tohru Utsunomiya, Masahiro Okamoto, Toshihumi Kameyama, Ayumi Matsuyama, Manabu Yamamoto, Megumu Fujiwara, Masaki Mori, Shiomi Aimitsu, Teruyoshi Ishida

研究成果: ジャーナルへの寄稿学術誌査読

47 被引用数 (Scopus)

抄録

Aim: To evaluate the impact of obesity on the postoperative outcome after hepatic resection in patients with hepatocellular carcinoma (HCC). Methods: Data from 328 consecutive patients with primary HCC and 60 patients with recurrent HCC were studied. We compared the surgical outcomes between the non-obese group (body mass index: BMI < 25 kg/m2) and the obese group (BMI ≥ 25 kg/m2). Results: Following curative hepatectomy in patients with primary HCC, the incidence of postoperative complications and the long-term prognosis in the non-obese group (n = 240) were comparable to those in the obese group (n = 88). Among patients with recurrent HCC, the incidence of postoperative complications after repeat hepatectomy was not significantly different between the non-obese group (n = 44) and the obese group (n = 16). However, patients in the obese group showed a significantly poorer long-term prognosis than those in the non-obese group (P < 0.05, five-year survival rate; 51.9% and 92.0%, respectively). Conclusion: Obesity alone may not have an adverse effect on the surgical outcomes of patients with primary HCC. However, greater caution seems to be required when planning a repeat hepatectomy for obese patients with recurrent HCC.

本文言語英語
ページ(範囲)1553-1558
ページ数6
ジャーナルWorld Journal of Gastroenterology
14
10
DOI
出版ステータス出版済み - 3月 14 2008
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 消化器病学

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