Impact of osteopenia in liver cirrhosis: Special reference to standard bone mineral density with age

Takeo Toshima, Tomoharu Yoshizumi, Toru Ikegami, Noboru Harada, Shinji Itoh, Yohei Mano, Takashi Motomura, Yuji Soejima, Yoshihiko Maehara

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

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Background/Aim: Computed tomography (CT) has recently been applied to measure bone mineral density (BMD). However, the definition of osteopenia, which means depletion of BMD, using CT remains controversial. The aim of this study was to establish formulae to calculate standard BMD. Patients and Methods: Fifty healthy donors for liver transplantation underwent CT. BMD was measured as crosssectional average pixel density (Hounsfield units) only in trabecular-bone at Th11 bottom. Validation was performed on another 50 healthy donors to check the accuracy of formulae for standard BMD. Results: Measured BMD was significantly correlated with age in both males and females (p<0.0001). The formulae to calculate standard BMD were 308.82-2.49 × Age in males and 311.84-2.41 × Age in females. Estimated BMD was significantly correlated with measured BMD in males and females (p<0.0001). Conclusion: Osteopenia can be defined by the difference between measured data and calculated data using our new formula based on each age.

元の言語英語
ページ(範囲)6465-6471
ページ数7
ジャーナルAnticancer research
38
発行部数11
DOI
出版物ステータス出版済み - 11 2018

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All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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