TY - JOUR
T1 - Impacts of Stressful Life Events and Traumatic Experiences on Onset of Obsessive-Compulsive Disorder
AU - Murayama, Keitaro
AU - Nakao, Tomohiro
AU - Ohno, Aikana
AU - Tsuruta, Sae
AU - Tomiyama, Hirofumi
AU - Hasuzawa, Suguru
AU - Mizobe, Taro
AU - Kato, Kenta
AU - Kanba, Shigenobu
N1 - Publisher Copyright:
© Copyright © 2020 Murayama, Nakao, Ohno, Tsuruta, Tomiyama, Hasuzawa, Mizobe, Kato and Kanba.
PY - 2020/12/3
Y1 - 2020/12/3
N2 - Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for comprehension of the pathophysiology of OCD. In the present study, we investigated the onset conditions of 281 patients with OCD and compared clinical characteristics among groups with or without stressful life events including traumatic experiences. As a result, 172 (61.2%) participants had experienced various stressful life events, and 98 (34%) participants had had traumatic experiences before the onset. Furthermore, the participants who had had stressful life events showed more contamination/fear symptoms compared with those without such life events. Meanwhile, the patients who had had specific traumatic experiences showed a tendency toward hoarding obsessions. To comprehend the pathophysiology of OCD, it is important to understand the stressful life events that precede its onset.
AB - Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for comprehension of the pathophysiology of OCD. In the present study, we investigated the onset conditions of 281 patients with OCD and compared clinical characteristics among groups with or without stressful life events including traumatic experiences. As a result, 172 (61.2%) participants had experienced various stressful life events, and 98 (34%) participants had had traumatic experiences before the onset. Furthermore, the participants who had had stressful life events showed more contamination/fear symptoms compared with those without such life events. Meanwhile, the patients who had had specific traumatic experiences showed a tendency toward hoarding obsessions. To comprehend the pathophysiology of OCD, it is important to understand the stressful life events that precede its onset.
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U2 - 10.3389/fpsyt.2020.561266
DO - 10.3389/fpsyt.2020.561266
M3 - Article
AN - SCOPUS:85098178654
VL - 11
JO - Frontiers in Psychiatry
JF - Frontiers in Psychiatry
SN - 1664-0640
M1 - 561266
ER -