Improvement of compressive properties of porous HA scaffold by introducing PCL secondary phase

Phanny Yos, Mitsugu Todo

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

Continuous porous hydroxyapatite (HA) scaffold has been considered to be used in bone tissue engineering. However, the low fracture property of HA scaffold has been a problem to be solved. In the present study, polycaprolactone (PCL) was introduced as a secondary phase into the porous structure of HA scaffold to improve the low fracture property. HA scaffolds were firstly fabricated using the template method. The HA scaffolds were then coated with PCL by changing the solution concentration from 1 to 5 wt%. Compression tests and SEM were done to examine the mechanical properties and the morphology of the two-phase composite scaffolds. It was found that the compression strength and modulus increased with increasing PCL concentration. It is also noted that PCL coating can greatly improve the brittleness of pure HA scaffolds. XRD test was also done to study the phase stability of HA and the two-phase scaffolds. There was no chemical reaction between PCL and HA observed by the XRD results. On the overall, these results indicated that PCL coating can effectively improve the low fracture property of pure HA scaffold and the two-phase scaffold could be a potential candidate for bone regeneration.

本文言語英語
ホスト出版物のタイトルFrontiers in Materials and Minerals Engineering
ページ96-102
ページ数7
DOI
出版ステータス出版済み - 1 8 2014
イベント5th Regional Conference on Materials Engineering and the 5th Regional Conference on Natural Resources and Materials 2013, RCM5 and RCNRM5 2013 - , マレーシア
継続期間: 1 22 20131 23 2013

出版物シリーズ

名前Advanced Materials Research
858
ISSN(印刷版)1022-6680

その他

その他5th Regional Conference on Materials Engineering and the 5th Regional Conference on Natural Resources and Materials 2013, RCM5 and RCNRM5 2013
Countryマレーシア
Period1/22/131/23/13

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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