Improvement of sensitivity of multisample biological immunoassay system using HTS SQUID and magnetic nanoparticles

A. Tsukamoto, K. Saitoh, N. Sugita, H. Kuma, Y. Sugiura, S. Hamaoka, N. Hamasaki, K. Enpuku

研究成果: Contribution to journalArticle査読

8 被引用数 (Scopus)

抄録

Recently, we have developed a prototype magnetic immunoassay system using a high temperature superconductor (HTS) superconducting quantum interference device (SQUID) to investigate the performance and usability of the magnetic immunoassay. In this study, we improved the immunoassay system to heighten the sensitivity of the immunoassay measurement. To reduce the SQUID-to-sample distance, we introduced a structure to compensate for thermal shrinkage in the cryostat and reduce the warpage of the window. The shape of pickup coil was also optimized to improve the field sensitivity. After these improvements, the magnetic signal intensity from Fe3O4 nanoparticles became about two times stronger than that achieved by our original system.

本文言語英語
ページ(範囲)975-978
ページ数4
ジャーナルPhysica C: Superconductivity and its applications
445-448
1-2
DOI
出版ステータス出版済み - 10 1 2006

All Science Journal Classification (ASJC) codes

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • エネルギー工学および電力技術
  • 電子工学および電気工学

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