Incidentally detected lesions on contrast-enhanced MR imaging in candidates for breast-conserving therapy: Correlation between MR findings histological diagnosis

Hidetake Yabuuchi, Toshiro Kuroiwa, Chie Kusumoto, Tatsuro Fukuya, Shinji Ohno, Yoichi Hachitanda

研究成果: ジャーナルへの寄稿評論記事

16 引用 (Scopus)

抄録

Purpose: To investigate the correlation between MR findings and the histological diagnosis of incidentally detected lesions in candidates for breast-conserving therapy. Materials and Methods: MR images of 299 patients with breast cancer were reviewed. Incidentally detected lesions were noted in 59 of 299 (20%) patients, and a histological diagnosis was obtained in 48 of 59 (81%) patients. There were 25 benign and 23 malignant lesions. The number, size, location, morphologic character, and kinetic curve assessment of the MR findings were analyzed. Statistical analyses were performed to determine whether any differences could be observed between benign and malignant lesions. Results: Lesions of over 10 mm tended to be malignant (11/16; 69%), whereas those equal or less than 5 mm tended to be benign (12/17; 71%; P < 0.05). Lesions in the same quadrant as the main lesion tended to be malignant (20/27.5; 73%), whereas those in a different quadrant tended to be benign (17.5/20.5; 85%; P < 0.001). Lesions with early peak of enhancement tended to be malignant (20/25; 80%), whereas those with persistent enhancement tended to be benign (20/23; 87%; P < 0.001). Conclusion: Incidentally detected lesions that are found in a different quadrant from the main lesion, are smaller than 10 mm in diameter, and show persistent enhancement on MR imaging suggest benign lesions. Therefore, patients with such lesions should avoid unnecessary surgical procedures unless lesions are proved to be malignant by cytology or biopsy.

元の言語英語
ページ(範囲)486-492
ページ数7
ジャーナルJournal of Magnetic Resonance Imaging
23
発行部数4
DOI
出版物ステータス出版済み - 4 1 2006

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Breast
Unnecessary Procedures
Therapeutics
Cell Biology
Breast Neoplasms
Biopsy

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

これを引用

Incidentally detected lesions on contrast-enhanced MR imaging in candidates for breast-conserving therapy : Correlation between MR findings histological diagnosis. / Yabuuchi, Hidetake; Kuroiwa, Toshiro; Kusumoto, Chie; Fukuya, Tatsuro; Ohno, Shinji; Hachitanda, Yoichi.

:: Journal of Magnetic Resonance Imaging, 巻 23, 番号 4, 01.04.2006, p. 486-492.

研究成果: ジャーナルへの寄稿評論記事

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abstract = "Purpose: To investigate the correlation between MR findings and the histological diagnosis of incidentally detected lesions in candidates for breast-conserving therapy. Materials and Methods: MR images of 299 patients with breast cancer were reviewed. Incidentally detected lesions were noted in 59 of 299 (20{\%}) patients, and a histological diagnosis was obtained in 48 of 59 (81{\%}) patients. There were 25 benign and 23 malignant lesions. The number, size, location, morphologic character, and kinetic curve assessment of the MR findings were analyzed. Statistical analyses were performed to determine whether any differences could be observed between benign and malignant lesions. Results: Lesions of over 10 mm tended to be malignant (11/16; 69{\%}), whereas those equal or less than 5 mm tended to be benign (12/17; 71{\%}; P < 0.05). Lesions in the same quadrant as the main lesion tended to be malignant (20/27.5; 73{\%}), whereas those in a different quadrant tended to be benign (17.5/20.5; 85{\%}; P < 0.001). Lesions with early peak of enhancement tended to be malignant (20/25; 80{\%}), whereas those with persistent enhancement tended to be benign (20/23; 87{\%}; P < 0.001). Conclusion: Incidentally detected lesions that are found in a different quadrant from the main lesion, are smaller than 10 mm in diameter, and show persistent enhancement on MR imaging suggest benign lesions. Therefore, patients with such lesions should avoid unnecessary surgical procedures unless lesions are proved to be malignant by cytology or biopsy.",
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T1 - Incidentally detected lesions on contrast-enhanced MR imaging in candidates for breast-conserving therapy

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AU - Yabuuchi, Hidetake

AU - Kuroiwa, Toshiro

AU - Kusumoto, Chie

AU - Fukuya, Tatsuro

AU - Ohno, Shinji

AU - Hachitanda, Yoichi

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N2 - Purpose: To investigate the correlation between MR findings and the histological diagnosis of incidentally detected lesions in candidates for breast-conserving therapy. Materials and Methods: MR images of 299 patients with breast cancer were reviewed. Incidentally detected lesions were noted in 59 of 299 (20%) patients, and a histological diagnosis was obtained in 48 of 59 (81%) patients. There were 25 benign and 23 malignant lesions. The number, size, location, morphologic character, and kinetic curve assessment of the MR findings were analyzed. Statistical analyses were performed to determine whether any differences could be observed between benign and malignant lesions. Results: Lesions of over 10 mm tended to be malignant (11/16; 69%), whereas those equal or less than 5 mm tended to be benign (12/17; 71%; P < 0.05). Lesions in the same quadrant as the main lesion tended to be malignant (20/27.5; 73%), whereas those in a different quadrant tended to be benign (17.5/20.5; 85%; P < 0.001). Lesions with early peak of enhancement tended to be malignant (20/25; 80%), whereas those with persistent enhancement tended to be benign (20/23; 87%; P < 0.001). Conclusion: Incidentally detected lesions that are found in a different quadrant from the main lesion, are smaller than 10 mm in diameter, and show persistent enhancement on MR imaging suggest benign lesions. Therefore, patients with such lesions should avoid unnecessary surgical procedures unless lesions are proved to be malignant by cytology or biopsy.

AB - Purpose: To investigate the correlation between MR findings and the histological diagnosis of incidentally detected lesions in candidates for breast-conserving therapy. Materials and Methods: MR images of 299 patients with breast cancer were reviewed. Incidentally detected lesions were noted in 59 of 299 (20%) patients, and a histological diagnosis was obtained in 48 of 59 (81%) patients. There were 25 benign and 23 malignant lesions. The number, size, location, morphologic character, and kinetic curve assessment of the MR findings were analyzed. Statistical analyses were performed to determine whether any differences could be observed between benign and malignant lesions. Results: Lesions of over 10 mm tended to be malignant (11/16; 69%), whereas those equal or less than 5 mm tended to be benign (12/17; 71%; P < 0.05). Lesions in the same quadrant as the main lesion tended to be malignant (20/27.5; 73%), whereas those in a different quadrant tended to be benign (17.5/20.5; 85%; P < 0.001). Lesions with early peak of enhancement tended to be malignant (20/25; 80%), whereas those with persistent enhancement tended to be benign (20/23; 87%; P < 0.001). Conclusion: Incidentally detected lesions that are found in a different quadrant from the main lesion, are smaller than 10 mm in diameter, and show persistent enhancement on MR imaging suggest benign lesions. Therefore, patients with such lesions should avoid unnecessary surgical procedures unless lesions are proved to be malignant by cytology or biopsy.

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