Inclusion body myositis associated with hepatitis C virus infection.

Y. Tsuruta, T. Yamada, T. Yoshimura, M. Satake, K. Ogata, T. Yamamoto, H. Furuya, J. Kira

研究成果: ジャーナルへの寄稿学術誌査読

15 被引用数 (Scopus)

抄録

Inclusion body myositis (IBM) is a chronic progressive inflammatory myopathy in elders. Three patients with chronic hepatitis C developed IBM. Their muscle biopsies were examined by polymerase chain reaction (PCR) for two patients and immunohistochemistry for three patients. The hepatitis C virus (HCV)-RNA genome was detected in one of the two patients. The degenerated and atrophic muscle fibers were immunoreactive for an anti-HCV antibody in all three patients. Immunoreactivity for an anti-HCV antibody was not apparent in the muscle specimen from an IBM patient without HCV infection. Our findings suggest that HCV infection is related to the pathogenesis in some cases of IBM.

本文言語英語
ページ(範囲)370-376
ページ数7
ジャーナルFukuoka igaku zasshi = Hukuoka acta medica
92
11
出版ステータス出版済み - 11月 2001

!!!All Science Journal Classification (ASJC) codes

  • 医学(全般)

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