Indirect measure of visceral adiposity ‘A body shape index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes

Ryotaro Bouchi, Masahiro Asakawa, Norihiko Ohara, Yujiro Nakano, Takato Takeuchi, Masanori Murakami, Yuriko Sasahara, Mitsuyuki Numasawa, Isao Minami, Hajime Izumiyama, Koshi Hashimoto, Takanobu Yoshimoto, Yoshihiro Ogawa

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

抄録

Objective: Among indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes. Methods: This is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness. Results: ABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate. Conclusions: ABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.

元の言語英語
記事番号e000188
ジャーナルBMJ Open Diabetes Research and Care
4
発行部数1
DOI
出版物ステータス出版済み - 1 1 2016
外部発表Yes

Fingerprint

Vascular Stiffness
Adiposity
Type 2 Diabetes Mellitus
Body Mass Index
Intra-Abdominal Fat
Waist Circumference
Cardiovascular Diseases
Pulse Wave Analysis
Subcutaneous Fat
Electric Impedance
Ankle
Arm
Cross-Sectional Studies
Population

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism

これを引用

Indirect measure of visceral adiposity ‘A body shape index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes. / Bouchi, Ryotaro; Asakawa, Masahiro; Ohara, Norihiko; Nakano, Yujiro; Takeuchi, Takato; Murakami, Masanori; Sasahara, Yuriko; Numasawa, Mitsuyuki; Minami, Isao; Izumiyama, Hajime; Hashimoto, Koshi; Yoshimoto, Takanobu; Ogawa, Yoshihiro.

:: BMJ Open Diabetes Research and Care, 巻 4, 番号 1, e000188, 01.01.2016.

研究成果: ジャーナルへの寄稿記事

Bouchi, R, Asakawa, M, Ohara, N, Nakano, Y, Takeuchi, T, Murakami, M, Sasahara, Y, Numasawa, M, Minami, I, Izumiyama, H, Hashimoto, K, Yoshimoto, T & Ogawa, Y 2016, 'Indirect measure of visceral adiposity ‘A body shape index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes', BMJ Open Diabetes Research and Care, 巻. 4, 番号 1, e000188. https://doi.org/10.1136/bmjdrc-2015-000188
Bouchi, Ryotaro ; Asakawa, Masahiro ; Ohara, Norihiko ; Nakano, Yujiro ; Takeuchi, Takato ; Murakami, Masanori ; Sasahara, Yuriko ; Numasawa, Mitsuyuki ; Minami, Isao ; Izumiyama, Hajime ; Hashimoto, Koshi ; Yoshimoto, Takanobu ; Ogawa, Yoshihiro. / Indirect measure of visceral adiposity ‘A body shape index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes. :: BMJ Open Diabetes Research and Care. 2016 ; 巻 4, 番号 1.
@article{196203f6d3374bc5919130a17a8e16c8,
title = "Indirect measure of visceral adiposity ‘A body shape index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes",
abstract = "Objective: Among indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes. Methods: This is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0{\%} female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness. Results: ABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate. Conclusions: ABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.",
author = "Ryotaro Bouchi and Masahiro Asakawa and Norihiko Ohara and Yujiro Nakano and Takato Takeuchi and Masanori Murakami and Yuriko Sasahara and Mitsuyuki Numasawa and Isao Minami and Hajime Izumiyama and Koshi Hashimoto and Takanobu Yoshimoto and Yoshihiro Ogawa",
year = "2016",
month = "1",
day = "1",
doi = "10.1136/bmjdrc-2015-000188",
language = "English",
volume = "4",
journal = "BMJ Open Diabetes Research and Care",
issn = "2052-4897",
publisher = "BMJ Publishing Group",
number = "1",

}

TY - JOUR

T1 - Indirect measure of visceral adiposity ‘A body shape index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes

AU - Bouchi, Ryotaro

AU - Asakawa, Masahiro

AU - Ohara, Norihiko

AU - Nakano, Yujiro

AU - Takeuchi, Takato

AU - Murakami, Masanori

AU - Sasahara, Yuriko

AU - Numasawa, Mitsuyuki

AU - Minami, Isao

AU - Izumiyama, Hajime

AU - Hashimoto, Koshi

AU - Yoshimoto, Takanobu

AU - Ogawa, Yoshihiro

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Objective: Among indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes. Methods: This is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness. Results: ABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate. Conclusions: ABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.

AB - Objective: Among indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes. Methods: This is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness. Results: ABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate. Conclusions: ABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.

UR - http://www.scopus.com/inward/record.url?scp=85022082711&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85022082711&partnerID=8YFLogxK

U2 - 10.1136/bmjdrc-2015-000188

DO - 10.1136/bmjdrc-2015-000188

M3 - Article

AN - SCOPUS:85022082711

VL - 4

JO - BMJ Open Diabetes Research and Care

JF - BMJ Open Diabetes Research and Care

SN - 2052-4897

IS - 1

M1 - e000188

ER -