Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media

Akira Hyodo, Keiji Iramina, Shoogo Ueno

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

2 被引用数 (Scopus)

抄録

In this study, we used a computer simulation to investigate the effects of the coil current waveform and direction on the excitation processes of the nerve axon in inhomogeneous and anisotropic conducting media in magnetic stimulation. We assumed that the nerve axon was located in the media with 2 regions having different conductivities or electrical anisotropy that simulate different tissue types. The distribution of induced electric fields was calculated with the finite element method (FEM). The nerve fiber was modeled after equivalent electrical circuits having active nodes of Ranvier. The direction of the coil current at the intersection of a figure-eight coil was assumed to flow perpendicular to the nerve axon. We observed the excitation threshold when the coil current waveform and direction are changed with varying the electrical properties such as tissue electrical conductivity and anisotropy. The simulation results show that the threshold decreases with the increase of conductivity ratio between 2 regions and it also depends on the coil current waveform and direction. Biphasic coil current has lower threshold than monophasic one when the current direction is the same in both waveforms. The results also suggest that the tissue anisotropy strongly affects the excitation threshold. The threshold increases with the increase of tissue anisotropic ratio of longitudinal direction to the transverse one respect to the nerve axon. The results in this study give useful information to explain the experimental results of the magnetic stimulation of human peripheral nervous systems and the theoretical model is applicable to understand the characteristics in magnetic stimulation of both peripheral and central nervous systems.

本文言語英語
ホスト出版物のタイトルProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
ホスト出版物のサブタイトルEngineering the Future of Biomedicine, EMBC 2009
出版社IEEE Computer Society
ページ6501-6504
ページ数4
ISBN(印刷版)9781424432967
DOI
出版ステータス出版済み - 2009
イベント31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, 米国
継続期間: 9月 2 20099月 6 2009

出版物シリーズ

名前Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

その他

その他31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
国/地域米国
CityMinneapolis, MN
Period9/2/099/6/09

!!!All Science Journal Classification (ASJC) codes

  • 細胞生物学
  • 発生生物学
  • 生体医工学
  • 医学(全般)

フィンガープリント

「Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル