Influence of maternal bifidobacteria on the establishment of bifidobacteria colonizing the gut in infants

Katsunaka Mikami, Hidenori Takahashi, Moto Kimura, Mitsuhiro Isozaki, Kunio Izuchi, Rumiko Shibata, Nobuyuki Sudo, Hideo Matsumoto, Yasuhiro Koga

研究成果: ジャーナルへの寄稿学術誌査読

49 被引用数 (Scopus)

抄録

The aim of this study was to examine the influence of maternal intestinal and vaginal bifidobacteria on the establishment of bifidobacteria colonizing the gut in infants. Fecal samples from 110 healthy pregnant mothers within 1 mo before delivery and their babies at 1 mo of age and 100 vaginal swabs from the mother within 7 d before delivery were collected at a maternity hospital in Fukuoka city, Japan. The fecal and vaginal samples were assayed by PCR to detect Bifidobacterium species and by real-time PCR assays to estimate the bifidobacterial number. The detection of Bifidobacterium breve in the mothers' feces was significantly associated with increases in both the bifidobacterial counts and number of Bifidobacterium species in the babies' feces. In addition, a cesarean section was significantly associated with both a decrease in the counts and diversity of bifidobacteria in the babies' feces. The number of Bifidobacterium species detected in the vaginal swabs of mothers were not associated with either the bifidobacterial counts or the diversity of bifidobacteria in the babies' feces. The most important determinants of intestinal bifidobacteria in infants were the colonization of B. breve in the mothers' gut and vaginal delivery.

本文言語英語
ページ(範囲)669-674
ページ数6
ジャーナルPediatric Research
65
6
DOI
出版ステータス出版済み - 6月 2009

!!!All Science Journal Classification (ASJC) codes

  • 小児科学、周産期医学および子どもの健康

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