Inhibitory effect of cadmium and mercury ions on transcription of the ada gene

Makoto Suzuki, Kazuhiko Takahashi, Yutaka Kawazoe, Kunihiko Sakumi, Mutsuo Sekiguchi

研究成果: Contribution to journalArticle査読

6 被引用数 (Scopus)

抄録

The effect of Cd2+ and Hg2+ on transcription of the ada gene was examined using an in, vitro system reconstituted with Ada protein and methylated DNA, together with their effect on methyltransferase activity of the Ada protein. Both Cd2+ and Hg2+ inhibited transcription of the ada gene over the doses which did not inhibit methyltransferse activity.

本文言語英語
ページ(範囲)1517-1521
ページ数5
ジャーナルBiochemical and Biophysical Research Communications
179
3
DOI
出版ステータス出版済み - 9 30 1991

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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