Initial tissue response to anti-washout apatite cement in the rat palatal region: Comparison with conventional apatite cement

Yoshiya Ueyama, Kunio Ishikawa, Takamitsu Mano, Takahiro Koyama, Hitoshi Nagatsuka, Tomohiro Matsumura, Kazuomi Suzuki

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

抄録

Initial tissue response to anti-washout apatite cement (aw-AC) in the palatal region was studied. Conventional apatite cement (c-AC) was employed as a control material. Bone defects generated in the rat palatal region, where complete hemostasis is difficult to effect, were filled with both cement types and examined histologically for up to 8 weeks. At 1-week postfilling, a portion of the c-AC had washed out, resulting in slight inflammation and severe foreign-body response. The degree of foreign-body response to c-AC was reduced over time; however, foreign-body response continued to be in evidence 8 weeks after surgery. As a result, poor bone formation was observed in the case of c-AC at 8 weeks post-surgery. In contrast, aw-AC set well, maintained its shape at implantation, and caused little foreign-body response. Osteoblasts were observed at 2 weeks following surgery. Moreover, the bone defect was completely covered with new bone at 8 weeks post-surgery. This observation suggests that aw-AC may be used without complication in cases where complete hemostasis is difficult to achieve, that is, where the use of c-AC is contraindicated.

元の言語英語
ページ(範囲)652-660
ページ数9
ジャーナルJournal of Biomedical Materials Research
55
発行部数4
DOI
出版物ステータス出版済み - 6 15 2001
外部発表Yes

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Apatites
Apatite
Rats
Cements
Tissue
Surgery
Bone
Defects
Osteoblasts

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Biomaterials

これを引用

Initial tissue response to anti-washout apatite cement in the rat palatal region : Comparison with conventional apatite cement. / Ueyama, Yoshiya; Ishikawa, Kunio; Mano, Takamitsu; Koyama, Takahiro; Nagatsuka, Hitoshi; Matsumura, Tomohiro; Suzuki, Kazuomi.

:: Journal of Biomedical Materials Research, 巻 55, 番号 4, 15.06.2001, p. 652-660.

研究成果: ジャーナルへの寄稿記事

Ueyama, Yoshiya ; Ishikawa, Kunio ; Mano, Takamitsu ; Koyama, Takahiro ; Nagatsuka, Hitoshi ; Matsumura, Tomohiro ; Suzuki, Kazuomi. / Initial tissue response to anti-washout apatite cement in the rat palatal region : Comparison with conventional apatite cement. :: Journal of Biomedical Materials Research. 2001 ; 巻 55, 番号 4. pp. 652-660.
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