Integrated comprehensive workbench for systems biology: Inference of genetic interaction and systems analysis of metabolic pathways

Masahiko Nakatsui, Yukihiro Maki, Tatsuya Sekiguchi, Masahiro Okamoto

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We propose integrated, comprehensive workbenches for systems identification and for systems analysis in systems biology. The former is named VoyaGene, which can analyze experimentally observed expression profiles by using and combining the five independent inferring models: clustering, threshold-test, Bayesian, multi-level digraph and S-system models. The latter is named WinBEST-KIT, which allow users to define original mathematical equations and to customize these equations very easily as user-defined reaction symbols. The following powerful system-analytical methods are prepared for systems analysis: time-course calculation, parameter scanning, estimation of the values of unknown kinetic parameters based on experimentally observed time-course data of reactants, dynamic response of reactants against virtual external perturbations and real-time simulation (virtual dry lab).

本文言語英語
ホスト出版物のタイトルWMSCI 2007 - The 11th World Multi-Conference on Systemics, Cybernetics and Informatics, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007 - Proc.
ページ7-12
ページ数6
出版ステータス出版済み - 12 1 2007
イベント11th World Multi-Conference on Systemics, Cybernetics and Informatics, WMSCI 2007, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007 - Orlando, FL, 米国
継続期間: 7 8 20077 11 2007

出版物シリーズ

名前WMSCI 2007 - The 11th World Multi-Conference on Systemics, Cybernetics and Informatics, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007 - Proc.
4

その他

その他11th World Multi-Conference on Systemics, Cybernetics and Informatics, WMSCI 2007, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007
Country米国
CityOrlando, FL
Period7/8/077/11/07

All Science Journal Classification (ASJC) codes

  • Artificial Intelligence
  • Information Systems

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