Integrated view of the human chromosome x-centric proteome project

Tadashi Yamamoto, Keiichi Nakayama, Hisashi Hirano, Takeshi Tomonaga, Yasushi Ishihama, Tetsushi Yamada, Tadashi Kondo, Yoshio Kodera, Yuichi Sato, Norie Araki, Hiroshi Mamitsuka, Naoki Goshima

研究成果: Contribution to journalReview article査読

4 被引用数 (Scopus)

抄録

This article introduces how the human chromosome Xcentric proteome project is carried out by the Japan Chromosome X Project Consortium. The inactivation of one of two chromosomes in female mammals and accumulation of genes related to neural/immune systems/tumor/testis are characteristic of chromosome X. In this Chromosome X Project, information on proteins translated from genes on chromosome X is collected by both mass spectrometry-and antibody-based proteomics. Information on the following resources is also provided: antibodies to proteins translated and full-length cDNAs transcripted from the chromosome X genes for recombinant proteins. The consortium aims to provide the following tools to search useful antibodies in the literature (Antibody Ranker), to find gene expression sites in microarray databases (Transcript Localizer) and to do advanced MRM analysis (information-based MRM).

本文言語英語
ページ(範囲)58-61
ページ数4
ジャーナルJournal of Proteome Research
12
1
DOI
出版ステータス出版済み - 1 4 2013

All Science Journal Classification (ASJC) codes

  • 生化学
  • 化学 (全般)

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