Interfacial Structures and Fibrinogen Adsorption at Blood-Compatible Polymer/Water Interfaces

Daiki Murakami, Shingo Kobayashi, Masaru Tanaka

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

抄録

The interfacial structures of a blood-compatible polymer, poly(2-methoxyethyl acrylate) (PMEA), and several analogues were investigated by atomic force microscopy (AFM). The blood-compatible polymers exhibited nanometer-scale protrusions that spontaneously and homogeneously formed at polymer/water and polymer/phosphate-buffered saline interfaces. AFM observation also revealed that fibrinogen adsorption occurred locally on the protrusions rather than uniformly at the interface, with the regions adjacent to the protrusions apparently preventing the adsorption of fibrinogen. The formation of these interfacial structures may be due to in-plane microphase separation of polymer and water at the interface.

元の言語英語
ページ(範囲)2122-2126
ページ数5
ジャーナルACS Biomaterials Science and Engineering
2
発行部数12
DOI
出版物ステータス出版済み - 12 12 2016

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Fibrinogen
Polymers
Blood
Adsorption
Water
Atomic force microscopy
Microphase separation
Phosphates

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering

これを引用

Interfacial Structures and Fibrinogen Adsorption at Blood-Compatible Polymer/Water Interfaces. / Murakami, Daiki; Kobayashi, Shingo; Tanaka, Masaru.

:: ACS Biomaterials Science and Engineering, 巻 2, 番号 12, 12.12.2016, p. 2122-2126.

研究成果: ジャーナルへの寄稿記事

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