Intracerebroventricular injection of glucagon-like peptide-1 decreases monoamine concentrations in the hypothalamus of chicks

T. Tachibana, S. Tanaka, M. Furuse, S. Hasegawa, H. Kato, K. Sugahara

研究成果: ジャーナルへの寄稿学術誌査読

5 被引用数 (Scopus)

抄録

1. We measured the concentrations of dopamine (DA), norepinephrine (NE), epinephrine (E) and 5-hydroxytryptamine (5-HT) in the hypothalamus of 21-d-old male brown-egg layer-type chicks after intracerebroventricular injection of glucagon-like peptide-1 (GLP-1). 2. The monoamine concentrations of the whole hypothalamus, paraventricular nucleus and lateral hypothalamic area were not significantly affected by GLP-1. 3. However, concentrations of DA, NE and E, but not 5-HT, in the ventromedial hypothalamic nucleus (VMH) were significantly decreased by GLP-1. 4. These observations suggest that the anorexigenic effect of GLP-I involves catecholaminergic systems in the VMH in the chick.

本文言語英語
ページ(範囲)122-126
ページ数5
ジャーナルBritish Poultry Science
43
1
DOI
出版ステータス出版済み - 3月 2002

!!!All Science Journal Classification (ASJC) codes

  • 食品科学
  • 動物科学および動物学

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